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Signs of a B12 deficiency include: pain tingling difficulty walking uncontrollable muscle movements confusion, forgetfulness, or memory loss changes in mental state or mood changes in smell or taste vision problems diarrhea weight loss glossitis, aka a painful, smooth, and red tongue If you have any of the above symptoms, talk with a doc

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Below 1 mg is supported by acute Phase 1 readings in lean Asian participants and real-world reports, but not by a chronic dosing trial